合成生物学平台

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谭在高

  • 教育背景

  • 工作经历

  • 研究方向

  • 代表性论文专著

  • 2011-2014   中国科学院大学  博士

  • 2008-2011   山东大学  硕士

  • 2004-2008   山东农业大学  学士

  • 2019-至今   上海交通大学生命科学技术学院  长聘教轨副教授

  • 2016-2019  美国莱斯大学化学与生物分子工程系      博士后

  • 2014-2016  美国爱荷华州立大学化学与生物工程系    博士后

  • 微生物代谢工程与合成生物学

  • Tan, Z; Clomburg J, Cheong S, Qian S and Gonzalez R. 2020. A polyketoacyl-CoA thiolase-dependent pathway for the synthesis of polyketide backbones. Nature Catalysis 3, p593-603.

  • Clomburg J*, Qian S*, Tan Z*, Cheong S* and Gonzalez R. 2019. The isoprenoid alcohol (IPA) pathway: a new paradigm for isoprenoid biosynthesis. PNAS 116 (26) 12810-12815. (*Co-first author)

  • Tan Z, Khakbaz P, Chen Y, Lombardo J, Yoon J, Shanks J, Klauda J, Jarboe L. 2017. Engineering phospholipids distribution improves Escherichia coli solvents tolerance and production of biorenewables. Metab Eng 44:1-12.

  • Tan, Z, Yoon J, Nielsen D, Shanks J, Jarboe L. 2016. Membrane engineering via trans unsaturated fatty acids production improves Escherichia coli robustness and production of biorenewables. Metab Eng 35:105-113.

  • Zhu X*, Tan Z*, Xu H, Chen J, Zhang X. 2014. Metabolic evolution of two reducing equivalent conserving pathways for high-yield succinate production in Escherichia coli. Metab Eng 24:87-96. (*Co-first author)

  • Tan Z, Clomburg J & Gonzalez R. 2018. Synthetic pathway for the production of olivetolic acid in Escherichia coli. ACS Synthetic Biology 7(8), 1886-1896.

  • Tan Z, Yoon J*, Chowdhury A, Burdick K, Jarboe L, Maranas C. & Shanks J. 2018. Engineering of E. coli inherent fatty acid biosynthesis capacity to increase octanoic acid production. Biotechnol Biofuels 2018 11:87.

  • Tan Z, Chen J*, Zhu X and Zhang X. 2016. Systematic engineering pentose phosphate pathway of Escherichia coli for improving succinate production. Biotechnol Biofuels 9:262.

  • Tan Z, Zhu X, Chen J, Li Q, Zhang X. 2013. Activating phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase in combination for improvement of succinate production. Appl Environ Microbiol 79:4838-4844.

  • Tan Z, Black W, Yoon J, Shanks J, & Jarboe L. 2017. Metabolic engineering of membrane proteins improves Escherichia coli membrane integrity and production of fatty acids. Microbial Cell Factories 28;16(1):38.