• 丁蓓，女，上海交通大学化学化工学院教授，超快科学中心PI。主要研究领域是超快光生物学，使用超快光谱技术（包括瞬态紫外可见吸收、瞬态中红外光谱和二维红外光谱）研究光酶和光受体蛋白的分子机制。2019-2021年期间受到海外高层次人才计划资助，担任科技部重点研发蛋白质专项青年科学家项目首席。

• 2009.7- 2014.8            密西根大学安娜堡分校

                                         物理化学博士2014, （导师： Zhan Chen教授）

                                         电子工程光学方向硕士2013, （双学位）

• 2005.7-2009.7             北京大学化学与分子工程学院

                                         化学学士2009

• 2024.12-至今          上海交通大学化学化工学院，教授

• 2023.12-至今          上海交通大学化学化工学院，长聘副教授

• 2017.9-2023.12         上海交通大学化学化工学院，长聘教轨副教授

• 2014.7-2017.8          美国宾夕法尼亚大学，博士后（导师：Feng Gai教授）

• 天然和人工光酶和光受体的反应动力学和结构动力学机制

• 围绕光生物体系动态机制发展混合飞秒脉冲中红外光谱技术

奖项情况

• 美国化学会物理化学杂志-物理化学分部讲座奖（2025）

• 入围全球超快女科学家大赛（2024）

• 上海交通大学第八届青教赛一等奖（2023）

在上海交大任课题组组长期间：

• 33. Wang, B.#, Dong, Y.#, Zhao, Z.#, Zhou, Z., Kang, X.-W., Li, Y., Ding, B.* Distinct Fermi Resonance Patterns of Weak Coupling in 2D-IR Spectra of 5-Cyanoindole Revealed by Isotope Labeling. J. Phys. Chem. B 2025, 129, 1036.

• 32. Zhou, Z.#, Chen, Z.#, Kang, X.-W.#, Ding, B.*, Zou, S., Tang, S., Zhou, Y., Wang, B., Zhong, D.* Elucidation of a Distinct Photoreduction Pathway in Class II Arabidopsis Thaliana Photolyase. Proc. Natl. Acad. Sci. U.S.A. 2025, 122, e2416284121.

• 31. Zhou, Y.#, Kang, X.-W.#, Zhou, Z., Chen, Z., Zou, S., Tang, S., Wang, B., Wang, K., Zhong, D.*, Ding, B.*. Unified Mechanism of Light-State BLUF Domain Photocycles by Capturing Proton Relay Intermediates. Ultrafast Sci. 2024, 4, 0072. (Cover paper)

• 30. Xu, W.*#, Mou, K.#, Lu, Z.#, Kang, X., Guo, Y., Ding, B., Chen, Z., Wang, Z.*, Wu, Q.*, Catalytic Promiscuity of Fatty Acid Photodecarboxylase Enables Stereoselective Synthesis of Chiral α-Tetralones, Angew. Chem. Int. Ed. 2024, e202412862.

• 29. Kang, X.-W., Wang, K., Zhang, X., Zhong, D.*, Ding, B.*, Elementary Reactions in the Functional Triads of the Blue-Light Photoreceptor BLUF Domain. J. Phys. Chem. B 2024, 128, 2065 (Invited Perspective, ACS Editor’s Choice, Cover paper)

• 28. Zhou, Y.#, Tang, S.#, Chen, Z., Zhou, Z., Huang, J., Kang, X.-W., Zou, S., Wang, B., Zhang, T., Ding, B.*, Zhong, D.*, Origin of the Multi-phasic Quenching Dynamics in the BLUF domains Across the Species. Nat. Commun., 2024, 15, 623.

• 27. Shi, Q., Kang, X.-W., Liu, Z., Sakthivel, P., Aman, H., Chang, R., Yan, X., Pang, Y., Dai, S.*, Ding, B.*, Ye, J.*, Single-Electron Oxidation-Initiated Enantioselective Hydrosulfonylation of Olefins Enabled by Photoenzymatic Catalysis, J. Am. Chem. Soc., 2024, 146, 2748. (Highly cited paper)

• 26. Wang, B., Zhou, Z., Zhang, Q., Dong, B., Kang, X.-W., Ding, B.*, Elucidating State-Specific Dynamics of 1La and 1Lb in Cyanoindole Derivatives Using UV/Vis Pump IR Detection. Chem. Phys., 2024, 576, 112095.

• 25. Zhang, Q., Zhou, Z., Deng, B., Wang, B., Kang, X.-W., Chen, J., Ding, B.*, Zhong, D.*, An Ultrafast Phototrigger of the Trp5CN–Trp Motif in a β-Hairpin Peptide. J. Chem. Phys., 2023, 158, 201102.

• 24. Hu, R., Zhou, Y., Lin, L., Ding, B.*, Lu, Q.*, Structure of the BLUF Protein TePixD Y8F Mutant. Progress in Biochemistry and Biophysics, 2023.

• 23. Chen, Z.#, Kang, X.-W.#, Zhou, Z., Zhou, Y., Tang, S., Zou, S., Wang, K., Huang, J., Ding, B.*, Zhong, D.*, Dissecting the Ultrafast Stepwise Bidirectional Proton Relay in a Blue-Light Photoreceptor. J. Am. Chem. Soc., 2023, 145, 3394.

• 22. Zhou, Z.#; Chen, Z.#; Kang, X.-W.; Zhou, Y.; Wang, B.; Tang, S.; Zou, S.; Zhang, Y.; Hu, Q.; Bai, F., Ding, B.* and Zhong, D.*, The Nature of Proton-Coupled Electron Transfer in a Blue Light Using Flavin Domain. Proc. Natl. Acad. Sci. U.S.A. 2022, 119, e2203996119.

• 21. Kang, X.-W.#, Chen, Z.#, Zhou, Z., Zhou, Y., Tang, S., Zhang, Y., Zhang, T., Ding, B.* and Zhong, D.*, Direct Observation of Ultrafast Proton Rocking in the BLUF Domain. Angew. Chem. Int. Ed. 2022, 61, e202114423.  (Frontispiece and Hot Paper)

• 20. Yang, J., Zhang, Y., He, T.F., Lu, Y., Wang, L., Ding, B.* and Zhong, D.*, Ultrafast Nonequilibrium Dynamics of Short-range Protein Electron Transfer in Flavodoxin. Phys. Chem. Chem. Phys. 2022, 24, 382-391.

• 19. Wang, S., Zhou, Q., Li, Y., Wei, B., Liu, X., Zhao, J., Ye, F., Zhou, Z., Ding, B. and Wang, P.*, Quinoline-Based Photolabile Protection Strategy Facilitates Efficient Protein Assembly. J. Am. Chem. Soc. 2022, 144, 3, 1232–1242.

• 18. Zhang, Q., Wang, B., Zhang, Y., Yang, J., Deng, B., Ding, B.* and Zhong, D.*, 2021. Probing Intermolecular Interactions of Amyloidogenic Fragments of SOD1 by Site-Specific Tryptophan and Its Noncanonical Derivative. J. Phys. Chem. B 2021, 125, 48, 13088-13098.

博士和博后期间：

• 17. Patel, H.#, Ding, B.#, Ernst, K., Shen, L., Yuan, W., Tang, J., Drake, L.R., Kang, J., Li, Y., Chen, Z. and Schwendeman, A. Characterization of apolipoprotein AI peptide phospholipid interaction and its effect on HDL nanodisc assembly. Int. J. Nanomedicine, 2019, 14, 3069. (#co-first author)

• 16. Ding, B.; Yang, L.; Mukherjee, D.; Chen, J.; Gao, Y.; Gai, F. Microscopic Insight into the Protein Denaturation Action of Urea and Its Methyl Derivatives. J. Phys. Chem. Lett. 2018, 9, 1–12.

• 15. Hilaire, M. R.#; Ding, B. #; Mukherjee, D.#; Chen, J.; Gai, F. Possible Existence of α-Sheets in the Amyloid Fibrils Formed by a TTR 105–115 Mutant. J. Am. Chem. Soc. 2018, 140 (2), 629–635. (#co-first author)

• 14. Ding, B.; Mukherjee, D.; Chen, J.; Gai, F. Do Guanidinium and Tetrapropylammonium Ions Specifically Interact with Aromatic Amino Acid Sidechains?  Proc. Natl. Acad. Sci. U.S.A.  2017, 114, 1003-1008

• 13. Ding, B.; Hilaire, M. R.; Gai, F. Infrared and Fluorescence Assessment of Protein Folding and Functional Dynamics. J. Phys. Chem. B (Feature Article), 2016, 120, 5103-5113

• 12. Ding, B.; Jasensky, J.; Li, Y.; Chen, Z. Engineering and Characterization of Peptides and Proteins at Surfaces and Interfaces: A Case Study in Surface-Sensitive Vibrational Spectroscopy. Acc. Chem. Res. 2016, 49, 1149-1157.

• 11. Ding, B.; Panahi, A.; Ho, J. J.; Laaser, J. E.; Brooks, C. L.; Zanni, M. T.; Chen, Z. Probing Site-Specific Structural Information of Peptides at Model Membrane Interface in Situ. J. Am. Chem. Soc. 2015, 137, 10190-10198.

• 10. Ding, B.; Tesmer, J.; Chen, Z. Unveiling the Membrane-Binding Properties of N-terminal and C-terminal Regions of G Protein-Coupled Receptor Kinase 5 by Combined Optical Spectroscopies. Langmuir 2013, 30, 823-831

• 9. Ding, B.; Laaser J. E.; Liu Y.; Wang P.; Zanni M. T., Chen, Z. Site-specific Orientation Determination of an α-helical Peptide Ovispirin-1 from Isotope labeled Sum Frequency Generation. J. Phys. Chem. B 2013, 117, 14625-14634

• 8. Ding, B.; Soblosky L., Nuygen, K.; Geng J.; Yu X.; Ramamoorthy A.; Chen, Z. Physiologically-Relevant Modes of Membrane Interactions by the Human Antimicrobial Peptide, LL-37, Revealed by SFG Experiments. Sci. Rep. 2013, 3, 1854

• 7. Ding, B.; Chen, Z. Molecular Interactions between a Cell Penetrating Peptide Pep-1 and Model Cell Membranes. J. Phys. Chem. B 2012, 116, 2545-2552

• 6. Ding, B.; Washington, V.; Dunietz, B. D. On the Conditions for Enhanced Transport Through Molecular Junctions Based on Metal Centers Ligated by Pyridazino-derived Ligands. Mol. Phys. 2010, 108, 2591-2599

• 5. Boughton, A.; Yang, P.; Tesmer, V.; Ding, B.; Tesmer, J.; Chen, Z. Heterotrimeric G protein β1γ2 Subunits Change Orientation Upon Complex Formation with G protein-Coupled Receptor Kinase 2 (GRK2) on a Model Membrane. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, E667-E673

• 4. Zhang, C.; Wang, J.; Ding, B.; Jasensky, J. Quantitative Spectral Analysis of Coherent Anti-Stokes Raman Scattering Signals: C-H Stretching Modes of the Methyl Group. J. Phys. Chem. B 2014, 118, 7647-7656

• 3. Zhang, C.; Wang, J.; Khmaladze, A.; Liu, Y.; Ding, B.; Jasensky, J.; Chen, Z. Examining Surface and Bulk Structures Using Combined Nonlinear Vibrational Spectroscopies. Opt. Lett. 2011, 36, 2272-2274

• 2. Chen, Z. Q.; Ding, F.; Hao, F.; Guan, M.; Bian, Z. Q.; Ding, B; Chen, F. F.; Huang C. H. Synthesis and Electroluminescent Property of Novel Europium Complexes with Oxadiazole Substituted 1,10-phenanthroline and 2,2 '-bipyridine Ligands. New. J. Chem. 2010, 34, 487-494.

• 1. Chen, Z. Q.; Ding, F.; Hao, F.; Bian, Z. Q.; Ding, B.; Zhu, Y. Z.; Chen, F. F.; Huang C. H. A Highly Efficient OLED based on  Terbium Complexes. Org. Electron. 2009, 10, 939-494.