DNA存储研究中心

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宋萍

  • 长聘教轨副教授

  • 电子邮箱:songpingsjtu@sjtu.edu.cn

  • 个人网页/课题组主页:

  • 教育背景

  • 工作经历

  • 研究方向

  • 荣誉奖励/承担项目

  • 代表性论文专著

  • 2006-2010 烟台大学,学士

  • 2010-2013 上海师范大学,硕士

  • 2013-2016 中国科学院上海应用物理研究所,博士

  • 2016-2017 莱斯大学,博士后

  • 2017-2021 莱斯大学,高级研究科学家

  • 2019-2021 NuProbe Inc (USA), 高级研究科学家(兼职)

  • 2021-至今  上海交通大学生物医学工程学院,长聘教轨副教授

  • DNA数据存储

  • 可编程核酸探针的设计及癌症诊断的应用

  • 主持国家自然科学基金面上项目。

  • 主持和参与科技部重点研发课题。

  • Yi Wu#, Jinxiao Guo#, Wenjun Li, Xuehao Xiu, Deepak Thirunavukarasu, Yudong Wang,  Kai Wang, Weiyu Chen, Chunhai Fan, David Yu Zhang, Ping Song*, Enhanced Detection of Novel Low-Frequency Gene Fusions via High-Yield Ligation and Multiplexed Enrichment Sequencing, Angewandte Chemie Internaltional Edition, 2024, e202316484.

  • Yunpei Si#, Xiawen Wang#, Xinglei Su#, Qiongzheng Hu, Qian Li, Chunhai Fan, David Yu Zhang, Yunshan Wang, Shihua Luo, Ping Song*, Extended Enrichment for Ultrasensitive Detection of Low-Frequency Mutations by Long Blocker Displacement Amplification, Angewandte Chemie Internaltional Edition, 2024, e202400551.

  • Haipei Zhao, Xuehao Xiu, Mingqiang Li, Shaobo Dai, Mingyang Gou, Leyang Tao, Xiaolei Zuo*, Chunhai Fan, Zhongqun Tian, Ping Song*, Programming Super DNA-Enzyme Molecules for On-Demand Enzyme Activity Modulation, Angewandte Chemie Internaltional Edition, 2023, e202214450.

  • Ping Song, Sherry X. Chen, Yan Helen Yan, Alessandro Pinto, Lauren Y. Cheng, Peng Dai, Abhijit A. Patel, and David Yu Zhang. "Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing." Nature Biomedical Engineering 5, no. 7 (2021): 690-701.

  • Ping Song, Lucia Ruojia Wu, Yan Helen Yan, Jinny X. Zhang, Tianqing Chu, Lawrence N. Kwong, Abhijit A. Patel, and David Yu Zhang. "Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics." Nature Biomedical Engineering (2022): 1-14.

  • Ping Song, Juwen Shen, Dekai Ye, Baijun Dong, Fei Wang, Hao Pei, Jianbang Wang et al. "Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework." Nature communications 11, no. 1 (2020): 1-10.

  • Ping Song, Dekai Ye, Xiaolei Zuo, Jiang Li, Jianbang Wang, Huajie Liu, Michael T. Hwang et al. "DNA hydrogel with aptamer-toehold-based recognition, cloaking, and decloaking of circulating tumor cells for live cell analysis." Nano letters 17, no. 9 (2017): 5193-5198.

  • Ye, Dekai#, Min Li#, Tingting Zhai#, Ping Song#, Lu Song, Hua Wang, Xiuhai Mao et al. "Encapsulation and release of living tumor cells using hydrogels with the hybridization chain reaction." Nature Protocols 15, no. 7 (2020): 2163-2185.

  • Romano, Gabriele, Pei-Ling Chen, Ping Song, Jennifer L. McQuade, Roger J. Liang, Mingguang Liu, Whijae Roh et al. "A preexisting rare PIK3CAE545K subpopulation confers clinical resistance to MEK plus CDK4/6 inhibition in NRAS melanoma and is dependent on S6K1 signaling." Cancer discovery 8, no. 5 (2018): 556-567.

  • Lin, Meihua, Ping Song, Guobao Zhou, Xiaolei Zuo, Ali Aldalbahi, Xiaoding Lou, Jiye Shi, and Chunhai Fan. "Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform." nature protocols 11, no. 7 (2016): 1244-1263.

  • Thirunavukarasu, Deepak, Lauren Y. Cheng, Ping Song, Sherry X. Chen, Mitesh J. Borad, Lawrence Kwong, Phillip James, Daniel J. Turner, and David Yu Zhang. "Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection." Genome biology 22, no. 1 (2021): 1-17.

  • Ping Song, Min Li, Juwen Shen, Hao Pei, Jie Chao, Shao Su, Ali Aldalbahi et al. "Dynamic modulation of DNA hybridization using allosteric DNA tetrahedral nanostructures." Analytical chemistry 88, no. 16 (2016): 8043-8049.

  • Zhu, Dan#, Ping Song#, Juwen Shen, Shao Su, Jie Chao, Ali Aldalbahi, Ziang Zhou et al. "PolyA-mediated DNA assembly on gold nanoparticles for thermodynamically favorable and rapid hybridization analysis." Analytical chemistry 88, no. 9 (2016): 4949-4954.

  • 樊春海; 左小磊; 宋萍; 一种用于肌氨酸的电化学检测方法, 2017-4-26, 中国, 2016110808061

  • 徐雪; 宋萍; 汪进平; 陈苗苗; 杨玉霞; 罗俊峰; 用于检测BRAF基因突变的引物组、试剂盒及方法, 2019-12-4, 中国, 2019112300368

  • 陈苗苗; 成昱璇; 宋萍; 徐雪; 汪进平; 罗俊峰; 用于检测EGFR基因突变的引物Blocker组、试剂盒 及方法, 2020-3-27, 中国, 2019113921252

  • 徐雪; 成昱璇; 宋萍; 汪进平; 陈苗苗; 王方金; 杨玉霞; 罗俊峰; 用于检测AML相关基因突变的引 物组、试剂盒及方法, 2020-4-10, 中国, 2019112359588

  • David Yu Zhang; Ping Song; Kerou Zhang; Amplicon comprehensive enrichment, 2020-6-26, 美国, 63/044,634.

  • David Yu Zhang; Ping Song; Xi Chen Systems and Methods for Allele Enrichment using Mult iplexed Blocker Displacement Amplification, 2019-8-29, WIPO, WO2019164885A1

  • David Yu Zhang; Deepak Thirunavukarasu; Yuxuan Cheng; Ping Song; Linear DNA assembly for nanopore sequencing, 2021-04-01, WIPO, WO2021108532A3

  • Amanda S.J. Schnepp; David Yu Zhang; Ping Song; Omid Veiseh; Siavash Parkhideh; Sudip Muk herjee; Maria Isabel Ruocco; Boram Kim; Yuxuan Cheng; High Throughput Genetic Barcoding and Anal ysis Methods, 2020-1-14, 美国, PCT/US2021/013395

  • Ping Song; Wenjun Li; David yu Zhang; Methods and Compositions for Sequencing and Fusion Detection Using Ligation Tail Adapters (LTA), 2020-12-29, 美国,

  • David Yu Zhang; Ping Song; Kerou Zhang; Amplicon comprehensive enrichment, 2020-6-26, 美国, 63/044,634. 

  • David Yu Zhang; Ping Song; Xi Chen; Systems and Methods for Allele Enrichment using Multiplexed Blocker Displacement Amplification, 2019-8-29, WIPO, WO2019164885A1

  • David Yu Zhang; Deepak Thirunavukarasu; Yuxuan Cheng; Ping Song; Linear DNA assembly for nanopore sequencing, 2021-04-01, WIPO, PCT/US2020/062201

  • Amanda S.J. Schnepp; David Yu Zhang; Ping Song; Omid Veiseh; Siavash Parkhideh; Sudip Muk herjee; Maria Isabel Ruocco; Boram Kim; Yuxuan Cheng; High Throughput Genetic Barcoding and Anal ysis Methods, 2020-1-14, 美国, PCT/US2021/013395

  • Ping Song; Wenjun Li; David yu Zhang; Methods and Compositions for Sequencing and Fusion Detection Using Ligation Tail Adapters (LTA), 2020-12-29, 中国, PCT/US2021/064534