Professor
Email address: shuquan@sjtu.edu.cn
EDUCATION
WORKING EXPERIENCE
RESEARCH
HONORS AND AWARDS
PUBLICATIONS
2004-2010 University of Michigan Doctor of Philosophy
2000-2004 Tsinghua University Bachelor of Science
2024-now Shanghai Jiao Tong University, School of Life Sciences and Biotechnology, Professor
2014-2024 East China University of Science and Technology, School of Biotechnology, Professor
2010-2013 Howard Hughes Medical Institute/ University of Michigan Research Associate
Protein folding biosensors, Chaperone biology and engineering, Enzyme engineering, Mechanisms and proteostasis of epigenetic enzymes
National Excellent Young Scientist
High-level Talent of Shanghai
He W.*, Yang Y., Qian Y., Chen Z., Zheng Y., Zhao W., Yan C., Guo Z., and Quan, S.* Fluorogenic sensing of amorphous aggregates, amyloid fibers, and chaperone activity via a near-infrared aggregation-induced emission-active probe. Aggregate (2024) 5(1): e412.
He, W.#, Li, X. #, Xue, H., Yang, Y., Mencius, J., Bai, L., Zhang, J., Xu, J., Wu, B.*, Xue, Y.*, and Quan, S.* Insights into the client protein release mechanism of the ATP-independent chaperone Spy. Nature Communications (2022) 13(1): 2818.
Li. Y.#, Zhao. L.#, Zhang. Y. #, Wu. P.#, Xu. Y., Mencius. J., Zheng. Y., Wang. X., Xu. W., Huang. N., Ye. X., Lei. M., Shi. P., Tian. C., Peng. C.*, Li. G.*, Liu. Z.*, Quan. S.*, Chen. Y.* Structural basis for product specificities of MLL family methyltransferases. Molecular Cell (2022) 82(20):3810-3825.e8.
Ren, C., Wen, X., Mencius, J., and Quan, S.* An enzyme-based biosensor for monitoring and engineering protein stability in vivo. Proc Natl Acad Sci U S A (2021) 118(13): e2101618118.
He, W. #, Yu, G. #, Li, T., Bai, L., Yang, Y., Xue, Z., Pang, Y., Reichmann, D., Hiller, S., He, L.*, Liu, M.*, and Quan, S.* Chaperone Spy Protects Outer Membrane Proteins from Folding Stress via Dynamic Complex Formation. mBio (2021) 12(5): e0213021.