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Man-Cheng TANG

  • Professor/Associate Professor/Assistant Professor/Lecturer | Postdocs

  • Email address: tangmc@sjtu.edu.cn

  • EDUCATION

  • WORKING EXPERIENCE

  • RESEARCH

  • HONORS AND AWARDS

  • PUBLICATIONS

  • 2004-2010  Shanghai Institute of Organic Chemistry, CAS  Doctor of Philosophy

  • 1999-2003  Wuhan University  Bachelor of Science

  • 2019-present  Shanghai Jiao Tong University, School of Life Sciences & Biotechnology, Associate Professor

  • 2014-2018  University of California, Los Angeles, Postdoctor

  • 2013-2014  Shanghai Institute of Organic Chemistry, CAS, Associate research fellow

  • 2010-2013  Shanghai Institute of Organic Chemistry, CAS, Research Assistant

  • Natural Product Biosynthesis and Synthetic Biology

  • The Shanghai High-level Talent Introduction Plan (2020)

  • Kong D.#, He Q.#, Lin D.-M., Zhang H., Chen L., Fan Y.*, Tang M.-C.*, Zou Y.* “Serine Hydrolase-Catalyzed Polyol Lipids are Necessary for Rodlet Layer Formation on the Cell Wall of Entomopathogenic Fungi.” J. Am. Chem. Soc. 2025, 147, 4701-4706.

  • Chen L., Wang X., Zou Y., Tang M.-C.* “Genome Mining of a Fungal Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid Megasynthetase Pathway to Synthesize a Phytotoxic N-Acyl Amino Acid.” Org. Lett. 2024, 26, 3597-3601.

  • Yu C.#, Chen L.#, Gao Y.-L., Liu J., Li P.-L., Zhang M.-L., Li Q., Zhang H.-D.*, Tang M.-C.*, Li L.* “Discovery and Biosynthesis of Macrophasetins from the Plant Pathogen Fungus Macrophomina phaseolina.” Front. Microbiol. 2022, 13, 1056392.

  • Tang M.-C., Shen C., Deng Z., Ohashi M., Tang Y.* “Combinatorial Biosynthesis of Terpenoids through Mixing-and-Matching Sesquiterpene Cyclase and Cytochrome P450 Pairs.” Org. Lett. 2022, 24, 4783-4787.

  • Liu L., Tang M.-C.*, Tang Y.* “Fungal Highly Reducing Polyketide Synthases Biosynthesize Salicylaldehydes that are Precursors to Epoxycyclohexenol Natural Products.” J. Am. Chem. Soc. 2019, 141, 19538-19541.

  • Tang M.-C.#, Fischer C. R.#, Chari J. V., Tan D., Suresh S., Chu A., Miranda M., Smith J., Zhang Z., Garg N., St Onge R. P.*, Tang Y.* “Thioesterase-catalyzed aminoacylation and thiolation of polyketides in fungi.” J. Am. Chem. Soc. 2019, 141, 8198-8206.

  • Tan D. #, Jamieson C. S. #, Ohashi M., Tang M.-C.*, Houk K. N.*, Tang Y.* “Genome-mined Diels-Alderase catalyzes the formation of the cis-octahydrodecalins of varicidin A and B.” J. Am. Chem. Soc. 2019, 141, 769-773.