• 2012-2017    Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Ph.D. in Biosynthesis

• 2008-2012   Sichuan University, B.S. in Pharmacy

• 2022-        School of Life Science & Biotechnology, Shanghai Jiao Tong University， Associated Professor

• 2020-2022   School of Life Science & Biotechnology, Shanghai Jiao Tong University， Assistant Professor

• 2017-2020   School of Life Science & Biotechnology, Shanghai Jiao Tong University， Post-doctoral Fellow

• Biosynthesis; Synthetic Biology

• Shanghai Oriental Talented Youth Project

• Morningstar Post-doctor of Shanghai Jiao Tong University (2019)

• Postgraduate Scholarship of Chinese Academy of Sciences

• Outstanding graduate of Sichuan Province, China (2012)

Selected Publications

• Lin, Z.#,*; Hu, Z. W. #; Zhou, L. J.; Liu, B. B.; Huang, X. W.；Deng, Z. X.; Qu, X. D.* A Large Conserved Family of Small-molecule Carboxyl Methyltransferases Identified from Microorganisms, Proc Natl Acad Sci. 2023, 120:e2301389120.

• Sun C. #; Tian W. #; Lin Z.*; Qu X. D.* Biosynthesis of pyrroloindoline-containing natural products. Nat Prod Rep. 2022, 39, 1721-1765.

• Lin, Z.#; Xue, Y. F.#, Liang, X. W.; Wang, J.; Lin, S. J.; Tao, J.; You, S. L.; Liu, W. Oxidative Indole Dearomatization for Asymmetric Furoindoline Synthesis by a Flavin-Dependent Monooxygenase Involved in the Biosynthesis of Bicyclic Thiopeptide Thiostrepton. Angew. Chem. Int. Ed. Angew. Chem. Int. Ed. Engl. 2021, 6, 8401-8405

• Lin, Z.; Ji, J.; Zhou, S. X.; Zhang, F.; Wu, J. Q.; Guo, Y. L.; Liu, W. Processing 2-Methyl-l-Tryptophan through Tandem Transamination and Selective Oxygenation Initiates Indole Ring Expansion in the Biosynthesis of Thiostrepton. J. Am. Chem. Soc. 2017, 139, 12105-12108.

• Wang, J.#; Lin, Z.#; Bai, X. B.; Tao, J.; Liu, W. Optimal Design of Thiostrepton-derived Thiopeptide Antibiotics and Their Potential Application against Oral Pathogens. Org. Chem. Front. 2019, 6, 1194-1199.

Published

• Lin, Z.#; He, Q. L.#; Liu, W. Bio-inspired Engineering of Thiopeptide Antibiotics advances the Expansion of Molecular Diversity and Utility. Curr. Opin. in Biotechnol. 2017, 48, 210-219.

• Lin, Z.; Qu, X. D. Emerging Diversity in Polyketide Synthase, Tetrahedron Lett., 2022, 110, 154183.

• Lin, Z.; Hu, Z. W.; Qu, X. D.; Lin. S. J. Advances and challenges in microbial production of benzylisoquinoline alkaloids. Synth. Biol. J., 2021, 2, 716-733

• Liu, J. Y.#; Lin, Z.#; Li, Y. Q.; Zheng, Q. F.; Chen. D. D.; Liu, W. Insights into the Thioamidation of Thiopeptins to Enhance the Understanding of the Biosynthetic Logic of Thioamide-Containing Thiopeptides. Org. Biomol. Chem. 2019, 17, 3732-3736.

• Liu, J. Y.#; Lin, Z.#; Chen, H.; Guo, H.; Tao, J.; Liu, W. Biosynthesis of the Central Piperidine Nitrogen Heterocycle in Series a Thiopeptides. Chin. J. Chem. 2019, 37, 35-41.