• 1997-2003   Florida State University   Doctor in Molecular Biophysics

• 1995-1997   Shanghai Jiao Tong University   Master in Molecular Biology

• 1991-1995   Shanghai Jiao Tong University   Bachelor in Molecular Biology & Bachelor in Applied Electronic Technology

• 2024-Present   Shanghai Jiao Tong University, School of Chemistry and Chemical Engineering, Professor

• 2024-Present   Shanghai Jiao Tong University, Zhangjiang Institute for Advanced Sciences, Professor

• 2009-Present   Chinese Academy of Sciences, Hefei Institutes of Physical Science, High Magnetic Field Laboratory, Professor

• 2006-Present   University of Science and Technology of China, School of Life Science, Professor

• 2003-2007   Vanderbilt University, School of Medicine, Postdoctoral Research Associate

• 1998-2003   National High Magnetic Field Laboratory, Center for Interdisciplinary of Magnetic Resonance, Research Assistant

Research Area: Bio-Spin Magnetic Resonance Research

Research Interests: Development of magnetic resonance (electron spin resonance (ESR), nuclear magnetic resonance (NMR), and magnetic resonance imaging (MRI)) equipment and methodologies, with a focus on their applications in chemical biology and synthetic biology.

1）Advancing ESR equipment and analytical methods to uncover the electron transfer and physicochemical mechanisms in enzymatic catalytic processes, thereby promoting synthetic biology research based on enzymatic catalysis.

2）Developing NMR methods to reveal dynamic conformational changes and chemical mechanisms across different functional states of enzymes.

3）Developing high-field MRI detection coils and analytical methods to conduct in vivo analysis of the pathology and pharmacology of significant diseases under native conditions.

• 2023, Chinese Peptide Symposium, Cathay Award

• 2022, The 9th China Overseas Chinese Community Contribution Award

• 2020, Special Allowance of the State Council of the People’s Republic of China for Natural Science Research

• 2019, Young and Middle-aged Experts with Outstanding Contributions under the National Talents Projects

• Yuanyuan Xu#, Hongwei Chen#, Lu Yu#, Xichao Peng, Jiawei Zhang, Zhongqiu Xing, Yuyan Bao, Aokun Liu, Yue Zhao, Changlin Tian*, Yong Liang* and Xiaoqiang Huang*, A Light-Driven Enzyme for Enantioselective Radical Acylation, Nature, 2024, 625(7993): 74-78

• Lu Yu*, Changlin Tian*, Electron Spin Resonance Analysis of Photoenzymatic Catalysis, National Science Review, 2024, 11, nwae095

• Beibei Zhao#, Jianqiang Feng#, Lu Yu#, Zhongqiu Xing, Bin Chen, Aokun Liu, Fulu Liu, Fengming Shi, Yue Zhao, Changlin Tian*, Binju Wang*, Xiaoqiang Huang*, Direct visible-light-excited flavoproteins for redox-neutral asymmetric radical hydroarylation, Nature Catalysis, 2023, 6: 996–1004

• Xu-Dong Kong*, Changlin Tian*, De novo discovery of bicycles, Nature Chemical Biology, 2025, 21, 29-31

• Wanning Zhang#, Jing Ai#, Tianwei Ouyang#, Lu Yu#, Aokun Liu, Lu Han*, Yingying Duan*, Changlin Tian*, Chaoyang Chu, Yanhang Ma*, Shunai Che*, Yuxi Fang*, Chiral Nanostructured Ag Films for Multicarbon Products from CO2 Electroreduction, Journal of the American Chemical Society, 2024, 146(41), 28214-28221

• Jian Cheng#, Nanxi Wang#, Lu Yu#, Yanmei Luo, Ao Kun Liu, Shuo Tang, Jin Yuan Xu, Yi Shuang Wang, Jiapeng Zhu, Andrey Lebedev*, Changlin Tian*, and Ren Xiang Tan*, Molecular Insights into the One-Carbon Loss Oxidation of Indole-3-Acetic Acid, ACS Catalysis, 2024, 14, 11, 8528–8540

• Fuying Kang#, Lu Yu#, Yan Xia#, Minling Yu, Lin Xia, Yuchuan Wang, Lin Yang, Tianyuan Wang, Weimin Gong, Changlin Tian*, Xiaohong Liu*, Jiangyun Wang*, Rational Design of a Miniature Photocatalytic CO2-Reducing Enzyme, ACS Catalysis, 2021, 11(9): 5628-5635

• Yongping Cui#, Jing Ai#, Yingying Duan#, Menghui Jia, Tianwei Ouyang, Aokun Liu, Lu Yu, Junhong Liu, Xi Liu, Chaoyang Chu, Yuanbo Li, Yanhang Ma, Liwei Chen, Lu Han*, Jinquan Chen*, Changlin Tian*, Shunai Che*, Yuxi Fang*, Enantioselective synthesis of amino acids by photocatalytic reduction of CO2 on chiral mesostructured ZnS, Chem, 2025, 10.1016/j.chempr.2024.102390

• Hongri Gong#, Jun Li#, Ao Xu#, Yanting Tang, Wenxin Ji, Ruogu Gao, Shuhui Wang, Lu Yu, Changlin Tian, Jingwen Li, Hsin Yung Yen, Sin Man Lam, Guanghou Shui, Xiuna Yang, Yuna Sun, Xuemei Li, Minze Jia, Cheng Yang, Biao Jiang, Zhiyong Lou, Carol V Robinson, Luet Lok Wong, Luke W Guddat, Fei Sun*, Quan Wang*, Zihe Rao*, An electron transfer path connects subunits of a mycobacterial respiratory supercomplex, Science, 2018, 362(6418): eaat8923

• Weiran Ge#, Cong Yu#, Jingjing Li#, Zhenyu Yu, Xiaorong Li, Yan Zhang, Chao-Pei Liu, Yingfeng Li, Changlin Tian, Xinzheng Zhang, Guohong Li, Bing Zhu*, Rui-Ming Xu*, Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase. Nature, 2023, 616 (7955), 176-182.