Professor
Email address: zouyike@sjtu.edu.cn
EDUCATION
WORKING EXPERIENCE
RESEARCH
HONORS AND AWARDS
PUBLICATIONS
2003–2010 B.Sc. and M.Sc., Chengdu University of Traditional Chinese Medicine
2012–2017 Ph.D., University of Pennsylvania, USA
2018–2022 Postdoctoral Researcher, University of California, Los Angeles (UCLA)
2021–2022 Lecturer, University of California, Los Angeles (UCLA)
2022–2023 Research Scientist, Lawrence Livermore National Laboratory
2024–Present Tenure-track Associate Professor, School of Pharmacy, Shanghai Jiao Tong University
AI-driven drug design
Enzyme design
Medicinal chemistry
Computational chemistry
2016 Chinese Government Award for Outstanding Self-financed Students Abroad
2021 National-level Young Overseas Talent Program
Gao, J.; Liu, S.; Zhou, C.; Lara, D.; Zou, Y.*; Hai, Y.* “A pyridoxal 5′-phosphate-dependent Mannich cyclase.” Nature Catalysis 2023, 1-11.
Zou, Y.*; Houk, K. N.*, “Mechanisms and Dynamics of Synthetic and Biosynthetic Formation of Delitschiapyrones: Solvent Control of Ambimodal Periselectivity” J. Am. Chem. Soc. 2021, 143 (30), 11734-11740.
Zou, Y.; Yang, S.; Sanders, J. N.; Li, W.; Yu, P.; Wang, H.; Tang, Z.; Liu, W.; Houk, K.N. “Computational Investigation of the Mechanism of Diels–Alderase PyrI4.” J. Am. Chem. Soc. 2020, 142, 20232-20239.
Zou, Y.; Wong, J.; Houk, K. N. “Computational exploration of a redox-neutral organocatalytic Mitsunobu reaction” J. Am. Chem. Soc. 2020, 142, 38, 16403–16408.
Zou, Y.‡; Wang, X. ‡; Sims, J.; Wang, B.; Pandey, P.; Welsh, C. L.; Stone, R. S.; Avery, M. A.; Doerksen, R. J.; Ferreira, D.; Anklin, C.; Valeriote, F. A.; Kelly, M.; Hamann, M. T. “Computationally-assisted discovery and assignment of a highly strained and PANC-1 selective alkaloid from Alaska’s deep ocean” J. Am. Chem. Soc. 2019, 141, 4338-4344.
Zou, Y.; Li, X.; Yang, Y.; Berritt, S.; Melvin, J.; Gonzales, S.; Spafford, M.; Smith, A. B. “Total synthesis of (−)-nodulisporic acids D, C, and B: evolution of a unified synthetic strategy” J. Am. Chem. Soc. 2018, 140, 9502.