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Chunyong DING
Professor
Email address: chunding@sjtu.edu.cn
EDUCATION
WORKING EXPERIENCE
RESEARCH
HONORS AND AWARDS
PUBLICATIONS
2005–2010 Ph.D. in Medicinal Chemistry, China Pharmaceutical University
2001–2005 B.Sc. in Pharmacy, China Pharmaceutical University
2020–Present Researcher, School of Pharmacy, Shanghai Jiao Tong University
2019–2020 Researcher, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2014–2019 Associate Researcher, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2013–2014 Assistant Researcher, Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Development of small molecule anti-cancer immunotherapies, drug target identification and validation, and molecular imaging probe development.
2019 Sanofi–Chinese Academy of Sciences Outstanding Young Talent Award
2019 First Prize, Youth Scholar Innovation Achievement Showcase, China Precision Medicine Conference
2010–2013 Postdoctoral Researcher, University of Texas Medical Branch, USA
Zhu Q#, Sun F#, Li T, Zhou M, Ye J, Ji A, Wang H*, Ding C*, Chen H, Xu Z*, Yu H*. Engineering oxaliplatin prodrug nanoparticles for second near Infrared fluorescence imaging-guided immunotherapy of colorectal cancer. Small 2021, 17(13):e2007882.
Tan J#, Wu B#, Chen T, Fan C, Zhao J, Xiong C, Feng C, Xiao R, Ding C*, Tang W*, Zhang A*. Synthesis and Pharmacological Evaluation of Tetrahydro-γ-carboline Derivatives as Potent Anti-inflammatory Agents Targeting Cyclic GMP-AMP Synthase. J. Med. Chem. 2021, 64(11):7667-7690.
Ding C, Song Z, Shen A, Chen T, Zhang A*, Small molecules targeting the innate immune cGAS‒STING‒TBK1 singling pathway. Acta Pharm. Sin. B, 2020, 10(12):2272-2298.
Xiao R#, Ding C#, Zhu H, Liu X, Gao J, Liu Q, Lu D, Zhang N*, Zhang A*, Zhou H*. Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer. Cancer Lett. 2020, 475:22-33.
Dang Y, Wang F, Li L, Lai Y, Xu Z*, Xiong Z, Zhang A, Tian Y, Ding C*, Zhang W*. An activatable near-infrared fluorescent probe for methylglyoxal imaging in Alzheimer's disease mice. Chem. Commun. 2020, 56(5):707-710.
Ding C*,#, Wang F#, Dang Y#, Xu Z*, Li L, Lai Y, Yu H, Luo Y, Huang R, Zhang A, Zhang W*. Imaging Tumorous Methylglyoxal by an Activatable Near-Infrared Fluorescent Probe for Monitoring Glyoxalase 1 Activity. Anal. Chem. 2019, 91(24):15577-15584.
Ding C#, Chen H#, Liang B, Jiao M, Liang G*, Zhang A*. Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury. Chem. Sci. 2019, 10, 4667-4672.
Ding C#, Tian Q#, Li J, Jiao M, Song S, Wang Y*, Miao Z-H*, Zhang A*. Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-Like Properties. J. Med. Chem. 2018, 61(3), 760–776.
Wang F, Yu S, Xu Z*, Li L, Dang Y, Xu X, Luo Y, Cheng Z, Yu H, Zhang W, Zhang A, Ding C*. Acid-Promoted D-A-D Type Far-Red Fluorescent Probe with High Photostability for Lysosomal Nitric Oxide Imaging. Anal. Chem. 2018, 90(13):7953-7962.
Li R,# Ding C,# Zhang J,# Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus A I, Sun S Y, Chen Z G, Sica G L, Ramalingam S S, Magis A T, Fu H, Khuri F R, Curran W J, Owonikoko T K, Shin D M, Zhou J*, Deng X* Modulation of Bax and mTOR for Cancer Therapeutics. Cancer Res. 2017, 77, 3001-3012.
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